I'm going through a phase of paralysis and probably just procrastinating by worrying over this.
I've come from a Node/Go background but really wanted to build out my new project in something extremely productive, rather than writing queries and validation over and over again. I'm decently familiar with Python, and Django is something that will do a lot for me and let me focus on features so I went with that.
What followed was me assuming I needed React, and spending a fair amount time learning about DRF and struggling to implement the correct Auth routes (Allauth) and obviously all the React/Redux boilerplate, with Typescript thrown in (I've used Typescript extensively, but it's not exactly low friction with React/Redux).
I've now wasted so much time.
Now the project is a Dev focused tool so will be behind a login screen, so no SEO concerns, but I thought React would mean it was ultra snappy but now I'm thinking I should just build this damn thing and worry about all that later.
I've even seen cases where you can have a hybrid/progressive app where some parts of the tool bring in React/Vue where required.
Edit; thank you all for your overwhelming encouragement to get back on track! It's clear that using React right now was a distraction.