What are the best ways to acquire users in web3?

Build a community, give them value, create opportunities for them to share that value with others in the web 3 scene. Your k factor is extremely crucial in Web3 marketing

For us as a niche B2B product, content marketing – putting out YouTube videos – happened to be quite effective. Second channel we launched, which currently is our main, as paid ads in Google. However, if you niche is more competitive, this may turn out to be very expensive.
When we've launched our token, influencer marketing has proven to be the most efficient channel.

Depending on your product/service, I'd recommend looking into influencer marketing. I think that would be very effective for web3.